发明名称 METHOD OF TREATING AND DIAGNOSING SLEEP DISORDERED BREATHING AND MEANS FOR CARRYING OUT THE METHOD
摘要 A method for treating of snoring, sleep apnea and other forms of sleep disordered breathing comprises administration to a patient of a therapeutically effective dose of an acetyl choline esterase inhibitor (CEI) over an appropriate period of time, such as a period substantially coinciding with the period of sleep of said patient. A CEI for use in this method is pyridostigmine or a pharmaceutically acceptable salt. A useful route of administration of CEI is per os, particularly for absorption in the oral cavity. Also described is the manufacture of a medicament for treatment of sleep disordered breathing by use of CEI, the administration of CEI in combination with deep sleep promoting agent, and a pharmaceutical composition containing CEI and a deep sleep promoting agent.
申请公布号 WO9722339(A1) 申请公布日期 1997.06.26
申请号 WO1996SE01677 申请日期 1996.12.17
申请人 HEDNER, JAN;KRAICZI, HOLGER 发明人 HEDNER, JAN;KRAICZI, HOLGER
分类号 A61K9/00;A61K31/00;A61K31/14;A61K31/17;A61K31/407;A61K31/4188;A61K31/44;A61K31/473;A61K31/536;A61K31/55;A61K31/662;A61K45/00;A61K45/06;A61P11/00;A61P25/20;(IPC1-7):A61K31/14;A61K31/435;A61K31/40;A61K31/395;A61K31/425;A61K31/66 主分类号 A61K9/00
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