PRODUCTION AND SCREENING PROCESS FOR PHYTOCHEMICAL PRODUCTION BY PLANT CELL CULTURES

摘要

A process for producing phytochemicals from plant cell cultures is provided. That process includes the step of culturing plant cells that produce a particular phytochemical in a multi-phase culture medium that includes an aqueous phase and a hydrophobic phase having a high partition coefficient for paclitaxel relative to the aqueous phase. The phytochemical is recovered from the hydrophobic phase. A process of screening plant cell cultures to plant cell lines that produce a particular phytochemical using the production process is also provided. A preferred phytochemical is paclitaxel.