| 发明名称 |
Fused-bicyclic lactams as interleukin-1 beta converting enzyme inhibitors |
| 摘要 |
Disclosed are compounds, compositions and methods for inhibiting interleukin-1 beta protease activity. The compounds, bicyclic derivatives of aldehydes and alpha -substituted methyl ketones, have the formula (A) set out herein.
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| 申请公布号 |
US5639745(A) |
申请公布日期 |
1997.06.17 |
| 申请号 |
US19950451108 |
申请日期 |
1995.05.25 |
| 申请人 |
SANOFI |
发明人 |
DOLLE, ROLAND E.;CHATURVEDULA, PRASAD V.;ROSS, TINA MORGAN;SCHMIDT, STANLEY J. |
| 分类号 |
C07D487/04;A61K31/535;A61K31/55;A61K38/00;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D471/04;C07D513/04;C07K5/02;C07K5/06;C07K5/078;(IPC1-7):A61K31/55 |
主分类号 |
C07D487/04 |
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