| 发明名称 |
APOPTOSIS INDUCED BY MONOCLONAL ANTIBODY ANTI-HER2 |
| 摘要 |
Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The antibodies are used to "tag" Her2 overexpressing tumors for elimination by the host immune system. Also disclosed are hybridoma cell lines producing the antibodies, methods for treating cancer using the antibodies, and pharmaceutical compositions. |
| 申请公布号 |
WO9720858(A1) |
申请公布日期 |
1997.06.12 |
| 申请号 |
WO1996US19289 |
申请日期 |
1996.12.04 |
| 申请人 |
AMGEN INC. |
发明人 |
ARAKAWA, TSUTOMU;KITA, YOSHIKO, A. |
| 分类号 |
C12N15/02;A61K38/00;A61K39/395;A61P35/00;A61P43/00;C07K14/82;C07K16/32;C07K16/46;C12N5/10;C12N5/20;C12P21/08;C12R1/91;(IPC1-7):C07K16/32 |
主分类号 |
C12N15/02 |
| 代理机构 |
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