发明名称 3-(4-SUBST.-PIPERIDINYL-1)-1-(3,4-DICHLOROPHENYL)PROPYL CARBAMATES AND UREAS AND DERIVATIVES AS NOVEL NEUROKININ ANTAGONISTS
摘要 Compounds of formula (I) wherein Q1, Q2, Q3, and Q4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists Substance P and NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula (I) and intermediates.
申请公布号 CA2234240(A1) 申请公布日期 1997.05.29
申请号 CA19962234240 申请日期 1996.11.15
申请人 ZENECA LIMITED 发明人 BERNSTEIN, PETER ROBERT;DEMBOFSKY, BRUCE THOMAS
分类号 C07D211/24;A61K31/00;A61K31/4427;A61K31/445;A61K31/4465;A61K31/4468;A61K31/45;A61K31/451;A61K31/4523;A61K31/505;A61K31/506;A61P11/00;A61P11/06;A61P43/00;C07D211/46;C07D211/52;C07D211/58;C07D211/62;C07D211/66;C07D211/76;C07D401/04;(IPC1-7):C07D211/58;C07D405/00;C07D409/00;C07D413/00;C07D471/04;A61K31/435;A61K31/495;A61K31/535;A61K31/54;C07D211/94 主分类号 C07D211/24
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