发明名称 |
3-(4-SUBST.-PIPERIDINYL-1)-1-(3,4-DICHLOROPHENYL)PROPYL CARBAMATES AND UREAS AND DERIVATIVES AS NOVEL NEUROKININ ANTAGONISTS |
摘要 |
Compounds of formula (I) wherein Q1, Q2, Q3, and Q4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists Substance P and NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula (I) and intermediates.
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申请公布号 |
CA2234240(A1) |
申请公布日期 |
1997.05.29 |
申请号 |
CA19962234240 |
申请日期 |
1996.11.15 |
申请人 |
ZENECA LIMITED |
发明人 |
BERNSTEIN, PETER ROBERT;DEMBOFSKY, BRUCE THOMAS |
分类号 |
C07D211/24;A61K31/00;A61K31/4427;A61K31/445;A61K31/4465;A61K31/4468;A61K31/45;A61K31/451;A61K31/4523;A61K31/505;A61K31/506;A61P11/00;A61P11/06;A61P43/00;C07D211/46;C07D211/52;C07D211/58;C07D211/62;C07D211/66;C07D211/76;C07D401/04;(IPC1-7):C07D211/58;C07D405/00;C07D409/00;C07D413/00;C07D471/04;A61K31/435;A61K31/495;A61K31/535;A61K31/54;C07D211/94 |
主分类号 |
C07D211/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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