发明名称 |
4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity |
摘要 |
4-phenyl-4-oxo-butanoic acid derivatives for use in the treatment of the human or animal body by therepy; particularly as kynurenine-3-hydroxylase inhibitors, in the prevention and/or treatment of a neurodegenerative disease wherein the inhibition of such an enyzme is needed. The present invention further comprises a selected class of the above mentioned 4-phenyl-4-oxo-butanoic acid derivatives, their pharmaceutically acceptable salts, a process for their preparation and pharmaceutical compositions containing them. |
申请公布号 |
AU7295196(A) |
申请公布日期 |
1997.05.29 |
申请号 |
AU19960072951 |
申请日期 |
1996.10.16 |
申请人 |
PHARMACIA & UPJOHN S.P.A. |
发明人 |
ANTONIO GIORDANI;PAOLO PEVARELLO;CARMELA SPECIALE;MARIO VARASI |
分类号 |
A61K31/00;A61K31/19;A61K31/192;A61K31/215;A61K31/216;A61P25/28;A61P43/00;C07C51/083;C07C51/353;C07C51/363;C07C51/367;C07C59/88;C07C59/90;C07C67/04;C07C67/307;C07C67/31;C07C67/333;C07C69/738;C07C205/56 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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