| 摘要 |
The invention relates to novel compounds of the formula (I), wherein R is (a) or (b), X is O or S and R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8> and n have the meaning given in claim 1. It also relates to the salts of said compounds. Said compounds and salts demonstrate endothelin receptor antagonistic properties.
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| 申请人 |
MERCK PATENT GMBH, 64293 DARMSTADT, DE |
发明人 |
MEDERSKI, WERNER, DR., 64390 ERZHAUSEN, DE;OSWALD, MATHIAS, DR., 64673 ZWINGENBERG, DE;DORSCH, DIETER, DR., 64372 OBER-RAMSTADT, DE;SCHMITGES, CLAUS J., DR., 64823 GROS-UMSTADT, DE;WILM, CLAUDIA, DR., 64367 MUEHLTAL, DE;CHRISTADLER, MARIA, 63322 ROEDERMARK, DE;ANZAHLI, SOHEILA, DR., 64297 DARMSTADT, DE |
