发明名称 Preparation of biologically active molecules by molecular imprinting
摘要 A method for preparing mimics of a wide variety of drugs and other biologically active molecules using molecular imprinting techniques, and the mimics produced thereby, is disclosed. Specifically, the mimic is designed by: (i) polymerization of functional monomers around a known drug or biologically active molecule (the template) that exhibits a desired activity; (ii) removal of the template molecule; and then (iii) polymerization of a second class of monomers in the void left by the template, to provide a new organic molecule which exhibits one or more desired properties which are similar to that of the template.
申请公布号 US5630978(A) 申请公布日期 1997.05.20
申请号 US19950476606 申请日期 1995.06.07
申请人 YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY OF JERUSALEM 发明人 DOMB, ABRAHAM J.
分类号 C07D207/16;C08F2/00;C08F220/58;(IPC1-7):C08J5/00 主分类号 C07D207/16
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