| 摘要 |
Benzenedicarboxylic acid diguanidides of formula (I) are new: one of R1, R2, R3 and R5 = -CO-N=C(NH2)2 and the others are as follows: R1 and R5 = H, 1-4C alkyl, F, etc.;R2 = H, halo, OH, CN, CF3, CO-N=C(NH2)2, 1-8C alkyl, 2-8C alkenyl, (CH2)mR14, SO2R22, CONR23R24, COR28, SO2NR29R30, OR35 or NR35R36; and R3 = H, SR25, OR25, NR25R26 or CR25R26R27; while R4 = e.g. CF3; m = 0-2; R14 = e.g. 3-8C cycloalkyl; R22, R28 = e.g. Me; R23, R24, R29, R30 = e.g. H; R35, R36 = H or 1-6C alkyl; or R35+R36 = e.g. 4-7 CH2 gps.; R25 = H, 1-8C alkyl, etc.; R26, R27 = H, 1-8C alkyl or groups as defined for R25. |
