Labelled boronic acid derivatives

摘要

The invention provides novel labelled boronic acid conjugates of formula (III) (wherein V is a reporter moiety; W2 is a bond or an organic linker moiety; W1 is a *SO2NR2, *CON2 or *CH2N(+)R2 2 group bound at the *-marked atom to the phenyl ring; R1 is hydrogen or an electron withdrawing substituent group; and each R2 independently is hydrogen or an optionally hydroxylated and optionally C1-6-alkoxylated C1-6-alkyl group) and salts thereof, e.g. for use in assays for cis-diols such as glycated blood proteins, having enhanced water-solubility and storage stability.