发明名称 |
STABLE AVIDIN COMPOSITION AND METHODS USING SAME |
摘要 |
Compositions and methods for avidin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels of avidin and may further include a bulking agent, e.g., maltose, and a protectant to maintain the stability and integrity of the avidin agarose during lyophilization and terminal sterilization processes. These compositions have applicability in any instance wherein avidin, agarose and/or the avidin/biotin technology are useful. In particular, the present compositions are useful in an enzyme capture system to prepare fibrin monomer useful for fibrin sealants.
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申请公布号 |
CA2237338(A1) |
申请公布日期 |
1997.05.15 |
申请号 |
CA19962237338 |
申请日期 |
1996.10.28 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
EDWARDSON, PETER A.D.;BURTON, STEVEN J.;PEARSON, JAMES C. |
分类号 |
C12N11/10;A61L2/00;A61L24/10;C07K1/22;C07K14/36;C07K14/465;C07K14/75;C07K17/10;C12N11/16;C12P21/06;(IPC1-7):C07K17/00;A61L2/08;G01N30/48 |
主分类号 |
C12N11/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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