发明名称 |
Method of treating retroviral infections in mammals |
摘要 |
The present invention is directed to the use of pharmaceutical compositions, containing an effective amount of topoisomerase I inhibitor such as camptothecin, useful in blocking both the initiation of infection and replication of retroviruses in host cells, thus reducing and eliminating retroviral production in infected cells. Use of such inhibitors provides as means of reducing or eliminating retroviral infections and their deleterious consequences in infected humans and animals.
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申请公布号 |
US5622959(A) |
申请公布日期 |
1997.04.22 |
申请号 |
US19950397936 |
申请日期 |
1995.03.03 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
PRIEL, ESTHER;BLAIR, DONALD G.;SHOWALTER, STEPHEN D. |
分类号 |
A61K31/00;A61K31/4745;A61K31/475;A61K38/21;(IPC1-7):A61K31/44 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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