摘要 |
<p>The present invention comprises human DNA compositions, including cDNA clones, with full sequences, called, KIRK-2 and KIRT-3, encoding proteins that confer potassium channel activity to membranes or recipient cell lines. The DNA compositions include structural genes coding for the potassium channel proteins, expression and replication plasmids or vectors containing the structural genes and host cells expressing those genes. Methods of screening compounds for potassium channel modulating activity are also described.</p> |