发明名称 Aza-anthracyclinone derivatives
摘要 PCT No. PCT/EP96/03237 Sec. 371 Date Feb. 9, 1998 Sec. 102(e) Date Feb. 9, 1998 PCT Filed Jul. 23, 1996 PCT Pub. No. WO97/06165 PCT Pub. Date Feb. 20, 1997Compounds of formula I wherein X1 and X2 are C=O, C=NH or CH2, X3 is CH2, CO, CHOH, wherein n=2 or, 3 or C=N(R9) wherein R9 is hydroxy or amino-aryl, and each of R1, R2, R3, R4, R5, R6, R7 and R8 are hydrogen, halogen or an organic residue, are useful in the treatment of amyloidosis. A process for their preparation and pharmaceutical compositions containing them are also described.
申请公布号 AU6735996(A) 申请公布日期 1997.03.05
申请号 AU19960067359 申请日期 1996.07.23
申请人 PHARMACIA S.P.A. 发明人 MICHELE CARUSO;DANIELA FIARDI;TIZIANO BANDIERA;JACQUELINE LANSEN;ANTONINO SUARATO
分类号 C07D451/02;A61K31/00;A61K31/435;A61P25/28;C07D209/56;C07D401/06;C07D451/00;C07D451/04;C07D471/08;C07H15/24 主分类号 C07D451/02
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