发明名称 PEGYLATION REAGENTS AND COMPOUNDS FORMED THEREWITH
摘要 Compounds are disclosed having the general formula R1-X-R2, wherein R1 and R2 are biologically active groups, at least one of which is polypeptidic. X is a non-peptidic polymeric group. R1 and R2 may be the same or different. Preferred R1 and R2 groups are TNF inhibitors.
申请公布号 EP0758906(A1) 申请公布日期 1997.02.26
申请号 EP19950923865 申请日期 1995.06.14
申请人 KOHNO, TADAHIKO;KACHENSKY, DAVE;HARRIS, MILTON 发明人 KOHNO, TADAHIKO;KACHENSKY, DAVE;HARRIS, MILTON
分类号 A61K38/00;A61K47/48;C07K14/47;C07K14/54;C07K14/715 主分类号 A61K38/00
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