发明名称 Extn. of a new form of collagen - by treating collagenous tissue with an alkaline hydroxide soln., neutralising and extn. with acid soln.
摘要 <p>Preparing extracted collagen comprises (a) treating collagenous tissue with an alkaline hydroxide soln., (b) neutralising the mass to obtain a pH of 5.5-9 and dividing the residue; (c) extracting the collagen from the residue in an acid environment, (d) centrifuging the mixt. and precipitating the collagen, (e) subjecting the collagenous mass obtd. to, (i) one or more washings with an alcohol, ketone or ether and drying to obtain an anhydrous collagen, or (ii) after washin with water, treating an aq. suspension with CO2 to obtain collagen as an aq. gel. Also claimed are: an extracted collagen form characterised by e.g. giving a negative toluidine blue reaction, or resistant to the proteolytic action of pancreatin for more than 24 hrs., an aq. based collagen gel comprising a collagen aq. suspension treated with CO2, and an aq. based collagen gel satd. with CO2.</p>
申请公布号 IT1267663(B1) 申请公布日期 1997.02.07
申请号 IT1993MI01254 申请日期 1993.06.11
申请人 EDMOND PHARMA S.R.L. 发明人 VANDONI GUIDO
分类号 A61K 主分类号 A61K
代理机构 代理人
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