| 摘要 |
PCT No. PCT/JP93/00109 Sec. 371 Date Jul. 21, 1994 Sec. 102(e) Date Jul. 21, 1994 PCT Filed Jan. 31, 1993 PCT Pub. No. WO93/15070 PCT Pub. Date Aug. 5, 19931-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methylaminopiperidin-1-yl)-4-oxoquinoline-3-carboxylic acid dihydrate having the following formula: <IMAGE> The crystal of this dihydrate exhibits excellent stability over the other crystal forms under various pharmaceutical formulation conditions such as moisture absorption and blending in solvents and, hence, it is a most advantageous crystal form in the manufacture of pharmaceuticals.
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