Disclosed is a hepatocyte bioreactor or bio-artifical liver which comprises a containment vessel having a perfusion inlet means and a perfusion outlet means; a matrix within said containment vessel so as to entrap hepatocyte aggregates within said containment vessel while allowing perfusion of said matrix. The invention is useful as an artificial liver.
申请公布号
DE69303779(T2)
申请公布日期
1997.01.16
申请号
DE1993603779T
申请日期
1993.01.06
申请人
MONSANTO CO., ST. LOUIS, MO., US
发明人
BARKER, GEORGE, EDWARD, ST. LOUIS, MO 63146, US;BECK, DALE, JOSEPH, IMPERIAL, MO 63052-2156, US;LI, ALBERT, PAK-HUNG, ST. LOUIS, MO 63021, US;WHITEHEAD, TIMOTHY, DANIEL, ST. LOUIS, MO 63143, US