CONFORMATIONALLY-RESTRICTED COMBINATORIAL LIBRARY COMPOSITION AND METHOD,申请号CA19962224086-传众专利搜索

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发明名称	CONFORMATIONALLY-RESTRICTED COMBINATORIAL LIBRARY COMPOSITION AND METHOD
摘要	Combinatorial libraries of different-sequence peptide members is disclosed. The libraries are comprised of stabilized, alpha-helical polypeptides having a similar tertiary structure but different amino acid residues at specific, "variable" positions in the sequence. The polypeptides are stabilized through coiled-coil interactions with other .alpha.-helical polypeptides and/or via intrahelical lactam bridges. Also disclosed are methods for using such libraries to screen for selected macromolecular ligands.
申请公布号	CA2224086(A1)	申请公布日期	1997.01.03
申请号	CA19962224086	申请日期	1996.06.14
申请人	PENCE	发明人	HODGES, ROBERT S.;HOUSTON, MICHAEL E., JR.
分类号	G01N33/53;B01J19/00;C07K1/04;C07K7/00;C07K14/00;C07K14/705;C40B40/10;C40B60/14;(IPC1-7):C07K2/00;C07K4/00;C12Q1/25;G01N33/566	主分类号	G01N33/53
代理机构		代理人
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