发明名称 |
Optically active phenol derivatives and preparation thereof |
摘要 |
An optically active tri-substituted methane compound having, as substituents, an aromatic ring group and a phenyl group having hydroxyl group at ortho or para position can be obtained by allowing a phenol compound unsubstituted at the ortho- or/and para-position to react with an optically active secondary carbinol compound having an aromatic ring group at the alpha-position in the presence of tri-substituted phosphine and diazodicarboxylate or diazodicarboxamide. These and other optically active tri-substituted methane compounds are useful as active ingredients for medicines or as intermediate compounds for preparing medicines.
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申请公布号 |
EP0751113(A1) |
申请公布日期 |
1997.01.02 |
申请号 |
EP19960202242 |
申请日期 |
1993.07.01 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
SHIRAISHI, MITSURU;FUKOMOTO, SHOJI |
分类号 |
C07C39/15;C07C59/56;C07C59/74;C07C59/88;C07C69/007;C07C69/732;C07C69/734;C07C69/738;(IPC1-7):C07C67/343;C07C67/293;C07C51/367;C07C37/16;C07C69/16;C07C69/767 |
主分类号 |
C07C39/15 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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