发明名称 USE OF AN IMMUNODEFICIENCY-VIRUS SUPPRESSING LYMPUSE OF AN IMMUNODEFICIENCY-VIRUS SUPPRESSING LYMPHOKINE (ISL) TO INHIBIT THE REPLICATION OF VIRUSEHOKINE (ISL) TO INHIBIT THE REPLICATION OF VIRUSES, IN PARTICULAR OF RETROVIRUSES S, IN PARTICULAR OF RETROVIRUSES
摘要 An isolated polypeptide which inhibits the replication of retroviruses in peripheral blood lymphocytes and i) is coded by the DNA sequence shown in SEQ ID NO:1 or complementary sequences, ii) is coded by DNA sequences which hybridize with SEQ ID NO:1 or SEQ ID NO:3 under stringent conditions, iii) is coded by DNA sequences which, if there was no degeneracy of the genetic code would hybridize under stringent conditions with the sequences defined in i) to ii), is useful as a therapeutic agent for the treatment of viral infections and benign and malignant proliferation diseases and as a diagnostic agent for said diseases.
申请公布号 WO9631607(A3) 申请公布日期 1996.12.27
申请号 WO1996EP01486 申请日期 1996.04.04
申请人 BUNDESREPUBLIK DEUTSCHLAND, VERTRETEN DURCH DEN BU;KURTH, REINHARD;BAIER, MICHAEL;METZNER, KARIN;WERNER, ALBRECHT 发明人 KURTH, REINHARD;BAIER, MICHAEL;METZNER, KARIN;WERNER, ALBRECHT
分类号 G01N33/53;A61K38/00;A61K38/19;A61K48/00;A61P31/12;A61P35/00;A61P37/04;C07K14/52;C07K14/54;C07K16/24;C12N1/21;C12N5/10;C12N15/09;C12N15/19;C12P21/02;C12Q1/68;G01N33/569;G01N33/68 主分类号 G01N33/53
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