发明名称 |
STABLE REAGENTS FOR THE PREPARATION OF RADIOPHARMACEUTICALS |
摘要 |
This invention provides novel reagents for the preparation of radiopharmaceuticals useful as imaging agents for the diagnosis of cardiovascular disorders, infection, inflammation and cancer, diagnostic kits comprising said reagents and intermediate compounds useful for the preparation of said reagents. The reagents are comprised of stable hydrazone modified biologically active molecules that react with gamma emitting radioisotopes to form radiopharmaceuticals that selectively localize at sites of diseases and thus allow an image to be obtained of the loci using gamma scintigraphy.
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申请公布号 |
CA2222183(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
CA19962222183 |
申请日期 |
1996.06.07 |
申请人 |
THE DUPONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
HARRIS, THOMAS DAVID;CHEESMAN, EDWARD HOLLISTER;RAJOPADHYE, MILIND;EDWARDS, DAVID SCOTT;LIU, SHUANG;SWORIN, MICHAEL |
分类号 |
A61K38/12;A61K49/04;A61K51/00;A61K51/04;A61K51/08;C07B59/00;C07D213/82;C07D257/00;C07D259/00;C07D277/60;C07D401/00;C07D401/12;C07D401/14;C07D413/12;C07K5/10;C07K5/103;C07K7/64;C07K14/75;C07K17/02;(IPC1-7):C07D401/12;C07D473/00;C07D475/00;C07D453/02;C07D471/04;C07D403/12;C07D405/12;C07D409/12;C07D417/12;C07K1/13;A61K31/44;C07D207/50;C07K7/56;C07D213/80 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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