发明名称 |
USE OF SQUALAMINE FOR THE MANUFACTURE OF A MEDICAMENT FOR INHIBITING NHE |
摘要 |
Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.
|
申请公布号 |
WO9640151(A1) |
申请公布日期 |
1996.12.19 |
申请号 |
WO1996US08954 |
申请日期 |
1996.06.07 |
申请人 |
MAGAININ PHARMACEUTICALS INC. |
发明人 |
ZASLOFF, MICHAEL |
分类号 |
A61K31/56;A61K31/575;A61P43/00;C07J9/00;(IPC1-7):A61K31/56 |
主分类号 |
A61K31/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|