| 发明名称 |
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| 摘要 |
Methods and compositions are provided for the purification of a protein identified as tumor necrosis factor from nonrecombinant and recombinant sources, the preparation of nucleic acid encoding this tumor necrosis factor and for its expression in recombinant hosts. This tumor necrosis factor is used in the therapeutic treatment of malignant tumors, either alone or in synergistic combination with an interferon. |
| 申请公布号 |
JP2557341(B2) |
申请公布日期 |
1996.11.27 |
| 申请号 |
JP19850149075 |
申请日期 |
1985.07.05 |
| 申请人 |
GENENTECH INC |
发明人 |
BARAA BUSHAN AGAAWARU;DEBITSUDO BANNOOMAN GETSUDERU;SAN HII RII;GUREN EBAN NEDOIN |
| 分类号 |
C12N15/09;A61K9/14;A61K35/02;A61K35/12;A61K35/14;A61K35/74;A61K38/00;A61K38/16;A61K38/21;A61P35/00;A61P43/00;C07H21/02;C07H21/04;C07K1/00;C07K1/18;C07K1/20;C07K14/00;C07K14/005;C07K14/195;C07K14/52;C07K14/525;C07K14/555;C07K14/57;C12N1/21;C12N15/00;C12P21/00;C12P21/02;C12Q1/68;C12R1/19;C12R1/865;C12R1/91;G01N33/68 |
主分类号 |
C12N15/09 |
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