发明名称 |
AZACYCLOALCANE DERIVATIVES, PREPARATION THEREOF AND THEIR APPLICATIONS IN THERAPY |
摘要 |
Azacycloalcane derivatives having general formula (I) wherein R1 and R2 represent a hydrogen atom, an alkyl group or a phenyl group, or R1 and R2 form together an oxo group, R3 is a hydrogen atom or an alkyl group, or R3 forms a methylene group, R4 is an aromatic group or, when R3 forms a methylene group, R4 is a phenylene group of which a carbon atom is bound to Y and another carbon atom adjacent to the former carbon atom is bound to said methylene group, R5 is either a group OR7 where R7 is a hydrogen atom or a benzyl group, or a group N4-methyl-piperazinyl, or else a group NHR8 wherein R8 is a hydroxyl, pyridinylmethyl or phenylmethyl group, A is an optionally substituted aromatic cycle, n is 1 or 2, X is CH, O or N, and Y is CH2, O or S, their preparation process and their applications in therapy.
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申请公布号 |
WO9634870(A1) |
申请公布日期 |
1996.11.07 |
申请号 |
WO1996FR00555 |
申请日期 |
1996.04.12 |
申请人 |
SYNTHELABO;BEDOYA ZURITA, MANUEL;DIAZ MARTIN, JUAN ANTONIO;DEL SOL MORENO, GREGORIO;MARTIN ESCUDERO PEREZ, ULPIANO;JIMENEZ BARGUENO, MARIA DOLORES;ROMANACH FERRER, MAGALI |
发明人 |
BEDOYA ZURITA, MANUEL;DIAZ MARTIN, JUAN ANTONIO;DEL SOL MORENO, GREGORIO;MARTIN ESCUDERO PEREZ, ULPIANO;JIMENEZ BARGUENO, MARIA DOLORES;ROMANACH FERRER, MAGALI |
分类号 |
C07D491/048;A61K31/40;A61K31/403;A61K31/4035;A61K31/404;A61K31/405;A61P3/08;A61P3/10;C07D209/42;C07D209/44;C07D217/06;C07D491/04;C07D491/056;C07D495/04;(IPC1-7):C07D495/04;A61K31/415 |
主分类号 |
C07D491/048 |
代理机构 |
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代理人 |
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