发明名称 |
PROCESS FOR PREPARING RACEMIC AND ENANTIOMERIC 1-(PYRIDYL)-2-CYCLOHEXYLETHYLAMINE |
摘要 |
This invention relates to the preparation of racemic and enantiomeric 1 (pyridyl)-2-cyclohexylethylamine and, in particular, the separation of (+)-(S)- or (-)-(R)-1-(2-pyridyl)-2-cyclohexylethylamine from a racemic mixture of -1- (R,S)-(2-pyridyl)-2-cyclohexylethylamine. According to this invention, the separation of a racemic mixture of 1-(pyridyl)-2-cyclohexylethylamine is carried out using 3-bromocamphor-8-sulfonic acid (BCSA). This invention also relates to a process for preparing a racemic mixture of 1-(pyridyl)-2-cyclohexylethylamine and free BCSA from readily available starting materials.
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申请公布号 |
CA2218480(A1) |
申请公布日期 |
1996.10.24 |
申请号 |
CA19962218480 |
申请日期 |
1996.03.18 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
GROZINGER, KARL GEORG |
分类号 |
C07B57/00;C07C309/25;C07D213/38;C07D405/12;(IPC1-7):C07D213/38;C07C303/02;C07D498/04;C07D513/04;C07D413/12;C07D417/12;C07C309/19 |
主分类号 |
C07B57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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