发明名称 |
NOVEL INTERMEDIATES AND PROCESS FOR THE MANUFACTURE OF CAMPTOTHECIN DERIVATIVES (CPT-11) AND RELATED COMPOUNDS |
摘要 |
This invention discloses and claims novel intermediates and procedures for the synthesis of camptothecin derivatives, such as irinotecan, and other compounds related to the synthesis of CPT-11 of formula (I). Related procedures and compounds are also disclosed, such as a novel method of making mappicine of formula (II).
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申请公布号 |
CA2214793(A1) |
申请公布日期 |
1996.10.10 |
申请号 |
CA19962214793 |
申请日期 |
1996.04.01 |
申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
SIH, JOHN C.;HENEGAR, KEVIN E. |
分类号 |
C07D491/147;A61K31/435;A61K31/436;A61K31/4738;A61P35/00;C07C251/26;C07C271/44;C07D213/30;C07D213/61;C07D213/64;C07D213/643;C07D213/79;C07D405/04;C07D471/04;C07D471/14;C07D491/04;C07D491/052;C07D491/14;C07D491/22;(IPC1-7):C07D471/14;C07D405/00;C07D473/00;C07D519/00;C07D401/06;C07D409/06;C07D413/06;C07D417/06;C12P17/12;C12P17/16 |
主分类号 |
C07D491/147 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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