摘要 |
The invention provides novel sulphonylurea, sulphonylthiourea and sulphonylguanidine compounds which have the ability to block potassium ion channels regulated by intracellular concentrations of ATP. Methods of synthesis, pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes, cardiac arrhythmias, ischaemic and hypoxic cardiovascular incidents, and cancers are also claimed.
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申请人 |
POLYCHIP PHARMACEUTICALS PTY. LTD.;THE UNIVERSITY OF SYDNEY;CHAMBERS, NOEL, JOHN;JOHNSTON, GRAHAM, ALLEN, ROSS |
发明人 |
CHAMBERS, NOEL, JOHN;JOHNSTON, GRAHAM, ALLEN, ROSS |