发明名称 |
DNA CHAIN USEFUL FOR XANTHOPHYLL SYNTHESIS AND PROCESS FOR PRODUCING XANTHOPHYLLS |
摘要 |
The following DNA chains relate to xanthophylls having a keto group, represented by astaxanthin, and the following technique relates to a genetically engineered production of xanthophylls: a DNA chain having a base sequence coding for a polypeptide having an enzymatic activity of converting the 4-methylene group of beta -ionone ring into a keto group; a DNA chain having a base sequence coding for a polypeptide having an enzymatic activity of converting the 4-methylene group of a 3-hydroxy- beta -ionone ring into a keto group; a DNA chain having a base sequence coding for a polypeptide having an enzymatic activity of adding a hydroxyl group to the 3-carbon atom of a 4-keto- beta -ionone ring; and a process for producing various xanthophylls, such a canthaxanthin and astaxanthin, by introducing the above DNA chain(s) into a suitable microorganism, e.g., Escherichia coli, followed by expression thereof. |
申请公布号 |
EP0735137(A1) |
申请公布日期 |
1996.10.02 |
申请号 |
EP19950903959 |
申请日期 |
1994.12.26 |
申请人 |
KIRIN BEER KABUSHIKI KAISHA;MARINE BIOTECHNOLOGY INSTITUTE CO., LTD. |
发明人 |
MISAWA, NORIHIKO KIBAN;KONDO, KEIJI KIBAN;KAJIWARA, SUSUMU KIBAN;YOKOYAMA, AKIHIRO |
分类号 |
C12N9/02;C12N15/53;C12P23/00 |
主分类号 |
C12N9/02 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|