发明名称 REST PROTEIN AND DNA
摘要 <p>The invention provides a substantially pure nucleic acid encoding a protein that inhibits the expression of neural proteins in non-neural tissues. The invention also provides a substantially pure nucleic acid encoding a protein that binds to a promoter sequence having at least about 90 % homology to nucleotides 6-28 of the RE1 sequence and acting to suppress the acitivity of a promoter having the promoter sequence. The invention further provides a substantially pure nucleic acid encoding a protein having at least about 85 % homology to at least one of the DNA binding domain or the suppressor domain of an animal RE1-Silencing Transcription factor. The invention also relates to the proteins so encoded.</p>
申请公布号 WO1996029433(A1) 申请公布日期 1996.09.26
申请号 US1996003940 申请日期 1996.03.22
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