摘要 |
A process for preparing 4,6-dichloropyrimidine comprising treating 4,6-dihydroxypyrimidine with phosphorus oxychloride in the presence of a saturated hindered amine, the hydrochloride salt of a saturated hindered amine, or an unsaturated 5-membered nitrogen containing ring or a mixture thereof, and separating 4,6-dichloropyrimidine from the reaction mixture so formed.
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申请人 |
ZENECA LIMITED;JONES, RAYMOND, VINCENT, HEAVON;WHITTON, ALAN, JOHN;BOYD, EWAN, CAMPBELL;RITCHIE, DAVID, JOHN |
发明人 |
JONES, RAYMOND, VINCENT, HEAVON;WHITTON, ALAN, JOHN;BOYD, EWAN, CAMPBELL;RITCHIE, DAVID, JOHN |