Menetelmä nitroglyseriiniä luovuttavan laastarin valmistamiseksi

摘要

PCT No. PCT/DE88/00478 Sec. 371 Date Jun. 9, 1989 Sec. 102(e) Date Jun. 9, 1989 PCT Filed Aug. 3, 1988 PCT Pub. No. WO89/01788 PCT Pub. Date Mar. 9, 1989.The invention relates to an apparatus for the controlled delivery or release of nitroglycerin to the human or animal skin, preferably in plaster form with a nitroglycerin-impermeable backing layer, a one or multiple-part reservoir containing a pressure sensitive adhesive nitroglycerin in uniform or irregular distribution and optionally a removable protective layer impermeable for nitroglycerin, the reservoir being produced using hol melt pressure sensitive adhesives with a processing temperature of 40 DEG to 80 DEG C., preferably 40 DEG to 60 DEG C. and in particularly preferred manner 40 DEG to 45 DEG C., a process for the production thereof and the use of the apparatus for therapeutic purposes in human and veterinary medicine.