发明名称 Specific glucocorticosteroid compound having anti-inflammatory activity
摘要 A compound of formula (I): wherein X represents O or S; R<SUB>1 </SUB>represents C<SUB>1-6 </SUB>alkyl, C<SUB>3-8 </SUB>cycloalkyl, C<SUB>3-8 </SUB>cycloalkylmethyl or C<SUB>3-8 </SUB>cycloalkenyl any of which optionally may be substituted by one or more methyl groups or halogen atoms or R<SUB>1 </SUB>represents aryl, substituted aryl, heteroaryl or substituted heteroaryl; R<SUB>2 </SUB>represents hydrogen, methyl, which may be in either the alpha or beta configuration, or methylene; R<SUB>3 </SUB>and R<SUB>4 </SUB>are the same or different and each independently represents hydrogen, halogen or a methyl group; and <img id="CUSTOM-CHARACTER-00001" he="3.13mm" wi="6.35mm" file="US07288536-20071030-P00001.TIF" alt="custom character" img-content="character" img-format="tif"/> represents a single or a double bond; or a physiologically acceptable salt or solvate thereof.
申请公布号 US7288536(B2) 申请公布日期 2007.10.30
申请号 US20040564325 申请日期 2004.07.09
申请人 GLAXO GROUP LIMITED 发明人 BIGGADIKE KEITH;JOHN MATTHEW PETER;NEEDHAM DEBORAH
分类号 A61K31/56;A61P5/44;C07D215/26;C07D233/54;C07D451/02;C07J1/00;C07J3/00 主分类号 A61K31/56
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