Verfahren zur Herstellung von 13C-markierten Verbindungen

摘要

A process for preparing a <1><3>C-labelled compound which comprises reacting an alcohol <1><3>C-labelled carbon source compound and a substrate in the presence of an enzyme system consisting of oxidase belonging to EC1 group and capable of converting the alcohol <1><3>C-labelled carbon source compound to an aldehyde <1><3>C-labelled carbon source compound, lyase belonging to EC4 group and capable of synthesizing a carbon-carbon bond and at least one of isomerases belonging to EC5 group and capable of isomerizing substrates to obtain a <1><3>C-labelled compound specifically labelled with <1><3>C in a specific carbon position.