发明名称 |
MR SPECTROSCOPY SYSTEM AND METHOD FOR DIAGNOSING PAINFUL AND NON-PAINFUL INTERVERTEBRAL DISCS |
摘要 |
An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine. |
申请公布号 |
US2016157745(A1) |
申请公布日期 |
2016.06.09 |
申请号 |
US201514872986 |
申请日期 |
2015.10.01 |
申请人 |
NOCIMED, LLC ;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
Peacock, III James Clayton;Claude John Patrick;Kane Paul Henry;Lotz Jeffrey C. |
分类号 |
A61B5/055;A61B5/00 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
1. An MRS system comprising an MRS pulse sequence, MRS signal processor, and MRS diagnostic processor, and which is configured to generate, acquire, and process an MRS spectrum representative of a region of interest in a body of a patient for providing diagnostically useful information associated with the region of interest. |
地址 |
Redwood City CA US |