A method for enhancing outflow of aqueous humor in treatment of glaucoma

摘要

Elevated intra-ocular pressure is reduced by administration directly to the eye of benzmetanide that inhibits function of a Na+-K+-2Cl-2 cotransporter mechanism discovered in trabecular meshwork cells of mammalian eyes. Benzmetanide is useful in treatment of diseases of the eye associated with elevated intra-ocular pressure, such as ocular hypertension and glaucoma.