发明名称 |
CHIMERIC CYTOKINES AND USES THEREOF |
摘要 |
Disclosed are chimeric proteins having a cytokine fused to an enzymatically inactive polypeptide which increases the circulating half-life of the cytokine. The chimeric proteins are useful for treating, inhibiting, or preventing a variety of conditions, including septic shock, granulomatous disorders, Type I diabetes, and various cancers (e.g., multiple myeloma) in a patient.
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申请公布号 |
CA2205572(A1) |
申请公布日期 |
1996.06.20 |
申请号 |
CA19952205572 |
申请日期 |
1995.12.12 |
申请人 |
BETH ISRAEL HOSPITAL ASSOCIATION |
发明人 |
ZHENG, XIN-XIAO;STEELE, ALAN;STROM, TERRY B. |
分类号 |
C12N15/09;A61K38/00;A61K38/19;A61K38/20;A61K38/21;A61K39/395;A61K47/48;A61P35/00;A61P43/00;C07K14/52;C07K14/525;C07K14/535;C07K14/54;C07K14/555;C07K14/76;C07K14/765;C07K16/18;C07K16/46;C07K19/00;C12N15/02;C12N15/62;C12P21/02;(IPC1-7):C07K19/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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