| 摘要 |
FIELD: organic chemistry. SUBSTANCE: method for production of isomer of compound having formula R-CH(CN)-Ror racemic modification which contains said isomer and its enantiomer is proposed here. In said formula each of R and Rmay represent any organic radical being directly or with the help of heteroatom bound with carbon atom having cyano group, proviso that at least one of R and Rcontains at least separated chiral center being stable during isomerization. Proposed method involves treatment of epimer of isomer or racemate which contains epimer and its enantiomer, said treatment is carried out in polar organic solvent or in suspension of polar organic liquid diluent. Epimer or racemate are partially soluble in said diluent, isomer or racemic modification which contains isomer and its enantiomer being less soluble in said solvent or in diluent then epimer of said isomer or than racemate which contains epimer of isomer and enantiomer of epimer. EFFECT: improves efficiency of method. |
