发明名称 |
Porous shaped delivery devices and method of producing thereof |
摘要 |
PCT No. PCT/US92/09273 Sec. 371 Date Jun. 1, 1994 Sec. 102(e) Date Jun. 1, 1994 PCT Filed Nov. 4, 1992 PCT Pub. No. WO93/12770 PCT Pub. Date Jul. 8, 1993.High strength, high porosity delivery devices have a shaped surface and disintegrate quickly in an aqueous medium. The devices can be prepared by disposing a formulation in a die to form a frozen predevice. A second die is contacted with the frozen formulation surface at a pressure and temperature for a time sufficient to locally momentarily liquify and shape the device surface. The shaping is followed by lyophilization.
|
申请公布号 |
US5516530(A) |
申请公布日期 |
1996.05.14 |
申请号 |
US19940244700 |
申请日期 |
1994.06.01 |
申请人 |
PFIZER INC. |
发明人 |
LO, JULIAN B.;MACKAY, GARY G.;PUZ, MICHAEL J. |
分类号 |
A61J3/10;A61K9/20;(IPC1-7):A61K9/44 |
主分类号 |
A61J3/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|