摘要 |
The present invention provides polyunsaturated fatty acid compounds having antimalarial and/or neutrophil stimulatory activity, or anti-inflammatory activity. The polyunsaturated fatty acids contain a 16-26 carbon chain, 3-6 double bands and are covalently coupled at the carboxylic acid group to an amino acid. It is preferred that the fatty acid contains 18-22 carbons and that the amino acid is glycine or aspartic acid. Preferred compounds are gamma -linolenic acid-glycine, alpha -linolenic acid-glycine, arachidonic acid-glycine, docosahexaenoic acid-glycine, eicosapentaenoic glycine, gamma -linolenic acid - aspartic acid, alpha -linolenic acid - aspartic acid, arachidonic acid - aspartic acid, eicosapentaenoic acid - aspartic acid and docosahexaenoic acid - aspartic acid.
|
申请人 |
PEPTIDE TECHNOLOGY LIMITED;WOMEN'S AND CHILDREN'S HOSPITAL ADELAIDE;SLEIGH, MERILYN, JOY;WIDMER, FRED;SCHOBER, PAUL, ADAM;FERRANTE, ANTONIO;POULOS, ALFRED;RATHJEN, DEBORAH, ANN |
发明人 |
SLEIGH, MERILYN, JOY;WIDMER, FRED;SCHOBER, PAUL, ADAM;FERRANTE, ANTONIO;POULOS, ALFRED;RATHJEN, DEBORAH, ANN |