发明名称 |
METHOD OF INHIBITING CONDITIONS ASSOCIATED WITH BRADYKININ |
摘要 |
A method of inhibiting a physiological condition associated with an excess of bradykinin comprising administering to a human in need thereof an effective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, -CH3, (a) or (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
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申请公布号 |
CA2203914(A1) |
申请公布日期 |
1996.05.02 |
申请号 |
CA19952203914 |
申请日期 |
1995.10.19 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
LUNN, WILLIAM HENRY WALKER;HOWBERT, JAMES JEFFRY;GEHLERT, DONALD RICHARD;BRUNS, ROBERT FREDERICK, JR. |
分类号 |
C07D333/56;A61K31/38;A61K31/381;A61K31/4025;A61K31/445;A61K31/4535;A61K31/505;A61K31/55;A61P11/00;A61P27/16;A61P29/00;A61P37/00;A61P43/00;(IPC1-7):A61K31/445;A61K31/40 |
主分类号 |
C07D333/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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