发明名称 METHOD OF INHIBITING CONDITIONS ASSOCIATED WITH BRADYKININ
摘要 A method of inhibiting a physiological condition associated with an excess of bradykinin comprising administering to a human in need thereof an effective amount of a compound having formula (I) wherein R1 and R3 are independently hydrogen, -CH3, (a) or (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
申请公布号 CA2203914(A1) 申请公布日期 1996.05.02
申请号 CA19952203914 申请日期 1995.10.19
申请人 ELI LILLY AND COMPANY 发明人 LUNN, WILLIAM HENRY WALKER;HOWBERT, JAMES JEFFRY;GEHLERT, DONALD RICHARD;BRUNS, ROBERT FREDERICK, JR.
分类号 C07D333/56;A61K31/38;A61K31/381;A61K31/4025;A61K31/445;A61K31/4535;A61K31/505;A61K31/55;A61P11/00;A61P27/16;A61P29/00;A61P37/00;A61P43/00;(IPC1-7):A61K31/445;A61K31/40 主分类号 C07D333/56
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