| 摘要 |
Bicyclic carboxamides (I) and their addn. salts are new. n = 1 or 2; R1 = furyl, thienyl or pyrimidinyl (all opt. substd. by 1-3C alkyl and/or 1-3C alkoxy), 2-4C alkyl, pyridyl, naphthyl or Ph; Ph = mono- di- or tri-substd. phenyl (opt. mono substd. by phenyl, halo or OR, and opt. mono-, di- or trisubstd. by 1-4C alkyl or 1-4C alkoxy (opt. monosubstd. by NR3R4)); R = allyl, propargyl or benzyl; R2 = 3-19C alkyl (opt mono-, di- or tri-unsatd., and opt. interrupted by 1 O or S), AAr, cyclohexyl, biphenyl or Het (opt. substd by 1-3C alkyl); Het = furyl, thienyl or pyridyl; A = 1-4C alkyl or 2-4C alkenyl; Ar = phenyl (opt. mono or di substd. by 1-3C alkyl, 1-3C alkoxy or halo) or cyclohexyl; R3, R4 = H or 1-6C alkyl; or NR3R4 = piperidino, morpholino or pyrrolidino; dotted line = opt. bond.
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| 申请人 |
DR. KARL THOMAE GMBH, 88400 BIBERACH, DE |
发明人 |
MAIER, ROLAND, DIPL.-CHEM. DR., 88400 BIBERACH, DE;HURNAUS, RUDOLF, DIPL.-CHEM. DR., 88400 BIBERACH, DE;WOITUN, EBERHARD, DIPL.-CHEM. DR., 88400 BIBERACH, DE;MUELLER, PETER, DIPL.-CHEM. DR., 88441 MITTELBIBERACH, DE;MARK, MICHAEL, DR., 88400 BIBERACH, DE;EISELE, BERNHARD, DIPL.-CHEM. DR., 88400 BIBERACH, DE |
