发明名称 |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
摘要 |
Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C6-C10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics
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申请公布号 |
US5512549(A) |
申请公布日期 |
1996.04.30 |
申请号 |
US19940324960 |
申请日期 |
1994.10.18 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
CHEN, VICTOR J.;DIMARCHI, RICHARD D.;SMILEY, DAVID L.;STUCKY, RUSSELL D.;KRIAUCIUNAS, AIDAS V. |
分类号 |
A61K38/26;A61K38/00;A61P3/08;A61P3/10;C07K14/575;C07K14/605;C12N15/16;(IPC1-7):A61K38/00 |
主分类号 |
A61K38/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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