| 发明名称 |
METHODS FOR TREATING RESISTANT TUMORS |
| 摘要 |
The present invention provides methods for reversing multidrug resistance in a resistant neoplasm by treating a mammal in need of said treatment with a substituded indole, benzofuran, benzothiophene, naphthalene, or dihydronaphthalene. This invention also provides methods for treating neoplasms in a mammal which comprises administering to a mammal in need of this treatment a substituted indole, benzofuran, benzothiophene, naphthalene, or dihydronaphthalene in combination with an oncolytic agent.
|
| 申请公布号 |
WO9611677(A1) |
申请公布日期 |
1996.04.25 |
| 申请号 |
WO1995US13036 |
申请日期 |
1995.10.13 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
CHANDRASEKHAR, SRINIVASAN;DANTZIG, ANNE, HOLLINS;SHEPARD, ROBERT, LEE;STARLING, JAMES, JACOB, II;WINTER, MARK, ALAN |
| 分类号 |
C07D333/56;A61K31/135;A61K31/195;A61K31/216;A61K31/34;A61K31/343;A61K31/38;A61K31/381;A61K31/40;A61K31/4025;A61K31/445;A61K31/4525;A61K31/4535;A61K31/55;A61K31/70;A61K45/06;A61P35/00;C07D209/12;C07D307/80;(IPC1-7):A61K31/135;C07C225/12;C07D207/08;C07D211/22;C07D223/04;C07D401/12;C07D403/12;C07D405/12;C07D409/12 |
主分类号 |
C07D333/56 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
