摘要 |
<p>An osteoplastic graft comprising a bone inducer supported on a composite porous body comprising a porous structure of a bioabsorbable hydrophilic material and a surface layer of a bioabsorbable polymeric material. Preferably, the hydrophilic material comprises at least one member selected from the group consisting of gelatin, hyaluronic acid and derivatives thereof, collagen and derivatives thereof, chitosan and derivatives thereof, and triethanolammonium alginate, while the polymeric material comprises at least one member selected from the group consisting of polylactic acid, polylactic acid-polyglycolic acid copolymer, and poly[bis(p-carboxyphenoxy)propane] anhydride-sebacid acid copolymer. As the graft is excellent in moldability and operability and has an internal structure suitable for in vivo bone neogenesis, bone grafting occurs not only at the periphery of the graft but also within the graft.</p> |