| 摘要 |
<p>The invention concerns compounds of formula (I), wherein each of G?1, G2 and G3¿ is CH or N; m is 1 or 2; R1 includes hydrogen, halogeno and (1-4C)alkyl; M1 is a group of formula: NR?2-L1-T1R3¿, in which R?2 and R3¿ together form a (1-4C)alkylene group, L1 includes (1-4C)alkylene, and T1 is CH or N; A may be a direct link; M2 is a group of the formula: (T2R4)r-L2-T3R5 in which R is 0 or 1, each of T?2 and T3¿ is CH or N, each of R?4 and R5¿ is hydrogen or (1-4C)alkyl, or R?4 and R5¿ together form a (1-4C)alkylene group, and L2 includes (1-4C)alkylene; M3 may be a direct link to X; X includes sulphonyl; and Q includes naphthyl and a heterocyclic moiety; or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use as antithrombotic or anticoagulant agents.</p> |
