摘要 |
New tricyclic cpds. of formula (I) are claimed. In (I), R = F, CN, Cl or CF3, or is defined as is R2; R2 = H, 1-20C alkyl, (with or without asymmetric C atom), and where one or more CH2 gps. (but not those directly linked to the 5-member ring) may be replaced by -O-, -S-, -CH=CH-, -C?=C-, cyclopropan-1,2-diyl, -Si(CH3)2, 1,4-phenylene, 1,4-cyclohexylene, 1,3-cyclopentylene, 1,3-cyclobutylene, or 1,3-dioxan-2,5-diyl, with the proviso that O and S may not be directly linked, and where one or more H atoms in the alkyl gp. may be substd. by F, Cl, Br or OR3 or by one cyclic gp. (optically active or racemic); ring B = gp. (i)-(v); A1 = 1,4-phenylene, 1,4-cyclohexylene, pyridine-2,5-diyl, pyrimidine-2,5-diyl, (1,3)-thiazole-2,5-diyl, or (1,3)-thiazole-2,4-diyl, where one or more H may be substd. by F, or (1,3,4)-thiadiazole-2,5-diyl; M1 = a single bond, -C?=C-, -CH2CH2-, -O-CO-, -CO-O-, -CO- or -OCH2-; m = 0 or 1.
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申请人 |
HOECHST AG, 65929 FRANKFURT, DE |
发明人 |
WINGEN, RAINER, DR., 65795 HATTERSHEIM, DE;MANERO, JAVIER, DR., 65931 FRANKFURT, DE |