| 发明名称 |
CHIMOPAPAINE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEREOF, PROCESS FOR PURIFICATION OF CHIMOPAPAINE, INHIBITING PEPTIDES AND CHROMATOGRAPHIC CARRIERS |
| 摘要 |
A pharmaceutical composition comprising purified chymopapain and a reducing agent is presented. The purified chymopapain in this composition has a specific activity against 1 mM of N- alpha -benzoyl-DL-arginine p-nitroanilide at 40 DEG C. and pH 6.8 of between 3,000 and 4,500 units per mg, and contains less than 0.2% each of papaya proteinase III (PPIII), papain, and papaya proteinase IV (PPIV). |
| 申请公布号 |
LT3827(B) |
申请公布日期 |
1996.03.25 |
| 申请号 |
LTIP1645 |
申请日期 |
1993.12.21 |
| 申请人 |
THE BOOTS COMPANY PLC |
发明人 |
BARRETT,ALAN JOHN;BUTTLE,DAVID JOHN;RICH,DANIEL HULBERT |
| 分类号 |
A61K38/46;A61K38/00;C07K;C07K1/22;C07K5/06;C07K5/065;C07K14/415;C07K14/81;C07K16/40;C07K17/10;C12N;C12N9/00;C12N9/50;C12N9/99;(IPC1-7):C07K3/20;A61K37/02;B01D15/04 |
主分类号 |
A61K38/46 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
