| 发明名称 |
Peptdidylhydroxylglycine N-C lyase and DNA coding therefor. |
| 摘要 |
<p>The invention concerns a peptidylhydroxyglycine N-C lyase (PHL) catalyzing the reaction R-GlyOH -> R-NH2 wherein R represents a peptide residue, and GlyOH represents an alpha -hydroxyglycine residue linked to the C-terminus of said peptide R by an amide bond, a recombinant DNA molecule coding for a PHL, a method for the preparation of such a recombinant DNA molecule, processes for the preparation of PHL from a natural source or by means of the said recombinant DNA molecule, and the use of PHL for the preparation of an amidated peptide R-NH2.</p> |
| 申请公布号 |
GR3018181(T3) |
申请公布日期 |
1996.02.29 |
| 申请号 |
GR19950403305T |
申请日期 |
1995.11.22 |
| 申请人 |
CIBA-GEIGY AG;JAPAT LTD |
发明人 |
IWASAKI, YASUNO;SHIMOI, HIROKO;SUZUKI, KENJI;GHISALBA, ORESTE, DR.;NISHIKAWA, YOSHIKI;KAWAHARA, TAKASHI;KANGAWA, KENJI |
| 分类号 |
C12N9/88;C07K1/107;C07K14/585;C12N1/21;C12N5/10;C12N9/02;C12N15/09;C12N15/53;C12N15/58;C12N15/60;C12P21/02;C12R1/19;(IPC1-7):C12N15/53;C07K14/00;C07K1/00 |
主分类号 |
C12N9/88 |
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