发明名称 NOUVEAUX DERIVES DE L'IMIDAZOLE, LEUR PROCEDE DE PREPARATION, LES NOUVEAUX INTERMEDIAIRES OBTENUS, LEUR APPLICATION A TITRE DE MEDICAMENTS ET LES COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT
摘要 Novel products of formula (I), wherein R1 is hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, alkylthio, formyl, cycloalkyl optionally interrupted by heteroatoms, R2 and R3 are halogen, mercapto, acyl, carboxy, nitro, cyano, amino, carbamoyl, R4, -OR4, and R4 are hydrogen, alkyl, alkenyl, alkynyl, acyl, amino, -(CH2)m1-S(O)m2-X-R10, wherein m1 = 0-4, m2 = 0-2, X is a single bond or -NH-, -NH-CO-, -NH-CO-NH- and R10 is alkyl, alkenyl or aryl, and Y is optionally substituted aryl, said products being obtained in all the isomeric forms, their salts, and their novel use as medicines.
申请公布号 FR2723370(A1) 申请公布日期 1996.02.09
申请号 FR19940009566 申请日期 1994.08.02
申请人 ROUSSEL UCLAF 发明人 HECKMANN BERTRAND;VEVERT JEAN PAUL;ZHANG JIDONG
分类号 A61K31/415;A61K31/4178;A61K31/422;A61P3/02;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P13/02;A61P15/00;A61P43/00;C07D233/84;C07D405/06 主分类号 A61K31/415
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